- Trillian
 - Instant messager system with support for AIM, ICQ, MSN, Yahoo!, and IRC. Multiple simultaneous logins allowed, skinnable interface using XML, multiple server support, dcc encryption, and more. - Jabber Inc.
- Commercializing an open source, XML-based instant messaging platform.
- WiredRed Software
- Providers of web conferencing and video conferencing software and services for business.
- Odigo
- Search for people by interests and connect to buddies from other instant messaging platforms.
- Face Time Communications
- Offers instant messaging for business, including surveillance for monitoring and auditing messages.
- visitalk.com
- Offers voicemail, instant voice and video messaging, and a directory of personal communications numbers.
- ActiveBuddy, Inc.
- Services include news, weather, and movie times via instant messaging.
- Lan Messaging Software
- Instant messaging communications software applications for the office network.
- PresenceWorks
- Develops and licenses tools for businesses, enabling them to communicate effectively with their buyers, suppliers, and colleagues.
- VyPRESS Research
- Creators of instant messaging software for LAN/WAN and intranet environments.
- Antepo
- Developers of multi-access (SMS, WAP, PocketPC, desktop) instant messaging platform for the mobile telecommunication and enterprise markets.
- MECA Communications
- Offers branded instant messaging solutions to entertainment entities and marketers.
- DataMate Global Communications Ltd
- Offering secure corporate instant messaging solutions, including scalable LAN/WAN messaging for the small office to the large enterprise.
- Chat Blazer
- Pendulab's chat and instant messaging software. Product features include integrated graphical console, CPU resource management, and image emoticons.
- IM-Age
- Software to secure all public IM platforms and bring them into compliance with corporate and industry regulations.
- MessageCast, Inc.
- Provides an automated messaging environment for popular IM and alert platforms.
- Interactive Networks, Inc.
- Developers of technology that allow the customisation of the user interface as well as the integration with clients' sites and current services.
- Invertix
- Provides products and services to deliver Internet content to wireless networks.
- Ecrio, Inc.
- Technology applications and infrastructure company providing rich instant messaging solutions. Customers include wireless carriers, ISPs, ASPs, and portals.
- Rapman
- Makers of RaptiveX, an ActiveX COM Object that Creates a Full Featured Instant Messenger and More.
- ScreenFIRE
- Secure, enterprise, real-time buddy-list/peoplebrowser/instant messaging for corporations, homes, and students.
- All Instant
- Instant messaging for business.
- WildSMS
- Freeware programme that delivers instant text messages, graphics, and ring tones from the user's PC to mobile phones and pagers.
- Progress SonicMQ
- A JMS compliant Java Messaging Server that provides developers with a features for event based communications between distributed applications.
- Hubz
- Specialises in web-based instant messaging software.
- Agoo
- Instant messenger that provides users access to chat history, friend lists, and user settings from anywhere.
- Link Messenger
- Customised Java real-time instant messaging system .
- Zimbra
- Offers an open source, next-generation collaboration and messaging software.
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